BRD2 Polyclonal Antibody

货号：PA5-83631

规格：100 µL

价格：6472

产品类型：标签抗体

品牌：Thermo Fisher

抗原：Recombinant protein corresponding to Human BRD2

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	一抗	同型对照：
浓度：	0.1 mg/mL	用法：	0.25-2 µg/mL(ICC);0.25-2 µg/mL（IF）；1:50-1:200(IHC(P));0.04-0.4 µg/mL(WB）

产品详细信息Immunogen sequence: SMPQEEQELV VTIPKNSHKK GAKLAALQGS VTSAHQVPAV SSVSHTALYT PPPEIPTTVL NIPHPSVISS PLLKSLHSAG P靶标信息This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.

数据：

BRD2 Antibody (PA5-83631) in IFImmunofluorescent analysis of BRD2 in U-2 OS cells using a BRD2 polyclonal antibody (Product # PA5-83631). The analysis shows localization to nuclear speckles. BRD2 Antibody (PA5-83631) in IHCImmunohistochemical analysis of BRD2 in human fallopian tube using a BRD2 polyclonal antibody (Product # PA5-83631). The analysis shows moderate nuclear positivity in glandular cells.

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