组蛋白乙酰化修饰,H4K8,单克隆抗体,BRD2 Monoclonal Antibody (7C1B10)

2024-10-24

BRD2 Monoclonal Antibody (7C1B10)

货号:MA5-31656

规格:100 µL

价格:4806

产品类型:标签抗体

品牌:Thermo Fisher

抗原:Purified recombinant fragment of human BRD2 (AA: 2

物种:其它

宿主:小鼠

抗体亚型:IgG2b, kappa

克隆号:7C1B10

荧光染料:其它

类型:一抗同型对照:
浓度: 1 mg/mL用法:1:10,000(ELISA);1:200-1:400(Flow);1:500-1:2000(WB)
靶标信息This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.
数据:

BRD2 Antibody (MA5-31656) in WBWestern blot analysis of BRD2 in C6 (1) and HeLa (2) cell lysate. Samples were incubated with BRD2 monoclonal antibody (Product # MA5-31656) using a dilution of 1:500-1:2000.

BRD2 Antibody (MA5-31656) in FlowFlow cytometry of BRD2 in HeLa cells (green). Sample was incubated with BRD2 monoclonal antibody (Product # MA5-31656) using a dilution of 1:200-1:400 followed by negative control (red).
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