Mouse CRP ELISA Kit ELISA试剂盒,Mouse CRP ELISA Kit/小鼠CRP ELISA试剂盒

2024-10-24

Mouse CRP ELISA Kit/小鼠CRP ELISA试剂盒

货号:EM20RB,EM20RBX5,EM20RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.15 ng/mL

检测范围0.15-40 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameCRP
Protein aliasesC-reactive protein, petaxin related

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesAI255847, Crp, Ptx1
Gene ID(Mouse) 12944
Gene symbolCrp
UniProt ID(Mouse) P14847
Mouse CRP quantitates mouse CRP in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse CRP.小鼠CRP定量测定血清,血浆,上清液中的小鼠CRP。该检测试剂盒将专门识别天然和重组小鼠CRP。Target information 靶标信息CRP (C-reactive protein) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. Eeach subunit is made up of 206 amino acids, and has a molecular weight of 24 kDa. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity, and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.CRP(C反应蛋白)是一种主要的环状五聚体急性期蛋白化合物,由五个相同的,非共价结合的,非糖基化的亚基组成。每个亚基由206个氨基酸组成,分子量为24 kDa。 CRP是由肝脏产生的,在体内发生炎症过程中,血浆水平急剧上升。 CRP是经典补体级联反应的引发剂,与多种核成分(染色质,组蛋白等)结合,在先天免疫中起重要作用,并介导与免疫前非特异性宿主抗性相关的活性。具体而言,响应损伤,感染或炎症,CRP增加了100-1000倍。 CRP是调渗的,是经典补体级联反应的引发剂,也是单核细胞/巨噬细胞的活化剂。 CRP还与包括染色质,组蛋白和snRNP在内的几个核成分结合,表明CRP可能在细胞坏死过程中起清除剂的作用。 CRP基于其识别宿主的外源病原体和受损细胞的能力,并通过与血液中的体液和细胞效应系统相互作用而启动病原体消除,从而参与了几种与宿主防御相关的功能。已显示基础CRP水平升高的患者患高血压和心血管疾病的风险增加。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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