Mouse DLL4 ELISA Kit ELISA试剂盒,Mouse DLL4 ELISA Kit/小鼠DLL4 ELISA试剂盒

2024-10-24

Mouse DLL4 ELISA Kit/小鼠DLL4 ELISA试剂盒

货号:EM21RB,EM21RBX5,EM21RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6327,28472,54564

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.2 ng/mL

检测范围0.2-50 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameDLL4
Protein aliasesDelta-like protein 4, Delta4, Drosophila Delta homolog 4

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesDelta4, Dll4
Gene ID(Mouse) 54485
Gene symbolDll4
UniProt ID(Mouse) Q9JI71
Mouse DLL4 quantitates mouse DLL4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse DLL4.小鼠DLL4定量分析血清,血浆,上清液中的小鼠DLL4。 该检测试剂盒将专门识别天然和重组小鼠DLL4。Target information 靶标信息Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1. DLL4 is expressed in the vasculature and plays a critical role in vascular development. It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network. DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation. This in turn leads to a decrease in tumor growth, with no apparent toxicity.Delta样配体4(DLL4),也称为Delta-4,是果蝇delta蛋白的同源物,并作为缺口受体Notch1的跨膜结合配体。 DLL4在脉管系统中表达,并在血管发育中起关键作用。 它是由血管内皮生长因子(VEGF)诱导的,它是负反馈调节剂,可调节血管生成的萌芽并促进分化血管网络的形成。 已经发现DLL4在透明细胞肾肿瘤和膀胱癌的肿瘤血管中强烈表达,并且对DLL4的抑制导致血管增殖增加但成熟不良。 反过来,这导致肿瘤生长减少,没有明显的毒性。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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