Mouse HGFR/MET ELISA Kit ELISA试剂盒,Mouse HGFR/MET ELISA Kit/小鼠HGFR / MET ELISA试剂盒

2024-10-24

Mouse HGFR/MET ELISA Kit/小鼠HGFR / MET ELISA试剂盒

货号:EM37RB,EM37RBX5,EM37RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6327,28472,54564

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.08 ng/mL

检测范围0.082-20 ng/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein namec-Met
Protein aliaseshepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, met proto-oncogene tyrosine kinase, proto-oncogene c-Met, scatter factor receptor, SF receptor, tyrosine-protein kinase Met

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesAI838057, c-Met, HGF, HGFR, Par4
Gene ID(Mouse) 17295
Gene symbolMet
Mouse HGFR/MET quantitates mouse HGFR/MET in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse HGFR/MET.小鼠HGFR / MET定量测定血清,血浆,上清液中的小鼠HGFR / MET。该检测试剂盒将专门识别天然和重组小鼠HGFR / MET。Target information 靶标信息MET is a tyrosine kinase receptor for the hepatocyte growth factor. It is linked to functions such as cell proliferation, scattering, morphogenesis, and survival. Ligand binding at the cell surface induces autophosphorylation of MET that provides docking sites for downstream signaling molecules. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.MET是肝细胞生长因子的酪氨酸激酶受体。它与细胞增殖,散射,形态发生和存活等功能有关。细胞表面的配体结合诱导MET自身磷酸化,从而为下游信号分子提供停靠位点。配体活化后,MET与PI3激酶亚基PIK3R1,PLCG1,SRC,GRB2和STAT3相互作用。相互作用导致信号级联的激活,包括RAS-ERK,PI3,激酶-AKT和PLCgamma-PKC。 MET在胚胎发育中发挥作用,包括胃形成,肌肉和神经元发育,血管生成和肾脏形成。它在成年人中也起着重要作用,包括伤口愈合,器官再生和组织重塑。 MET与胃癌,肾癌和乳腺癌有关。因此,使其成为癌症治疗和诊断测试的目标。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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