Mouse Activin A ELISA Kit ELISA试剂盒,Mouse Activin A ELISA Kit/小鼠激活素A ELISA试剂盒

2024-10-24

Mouse Activin A ELISA Kit/小鼠激活素A ELISA试剂盒

货号:EM3RB,EM3RBX5,EM3RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:小鼠

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

0.5 pg/mL

检测范围0.5-100 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameActivin A
Protein aliasesActivin beta-A chain, Inhibin beta A chain

物种(Tested)

小鼠

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesInhba
Gene ID(Mouse) 16323
Gene symbolInhba
UniProt ID(Mouse) Q04998
Mouse Activin A quantitates mouse Activin A in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Activin A.小鼠激活素A定量检测血清,血浆,上清液中的小鼠激活素A。该检测试剂盒将专门识别天然和重组小鼠激活素A。Target information 靶标信息Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Activin A mutations are associated with fibrodysplasia ossificans progressive.激活素是二聚体生长和分化因子,属于结构相关信号蛋白的转化生长因子-β(TGF-beta)超家族。激活素通过受体丝氨酸激酶的异聚复合物发出信号,所述受体丝氨酸激酶包括至少两种I型(I和IB)和两种II型(II和IIB)受体。这些受体都是跨膜蛋白,由具有半胱氨酸富集区的配体结合细胞外结构域,跨膜结构域和具有预测的丝氨酸/苏氨酸特异性的胞质结构域组成。 I型受体对于信号转导至关重要。 II型和II型受体对于结合配体和I型受体的表达是必需的。 I型和II型受体在配体结合后形成稳定的复合物,导致I型受体被II型受体磷酸化。激活素A突变与进行性骨化增生有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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