GadoSpin M 胞外核磁共振成像(MRI)造影剂 130-095-134 MB,GadoSpin M /胞外核磁共振成像(MRI)造影剂

2024-10-24

GadoSpin M /胞外核磁共振成像(MRI)造影剂

货号:130-095-134,130-095-135

规格:for 5 injections,for 5×5 injections

价格:0,0

产品类型:小动物造影剂

品牌:Miltenyi

GadoSpin M is a gadolinium-based contrast agent of low molecular weight specifically formulated for pre-clinical magnetic resonance imaging (MRI).GadoSpin M increases the signal intensity in T1-weighted MRI due to a shortening of the spin-lattice relaxation time (T1).Upon intravenous injection, GadoSpin M is rapidly distributed in the extracellular space. No significant plasma protein–binding can be observed and the stable complex is excreted unchanged via glomerular filtration (kidneys) within hours.Gd-DTPA does not penetrate the intact blood brain barrier and is, in fact, used in clinical practice for imaging of brain tumors.

GadoSpin M是一种低分子量的钆螯合造影剂,专门用于临床前磁共振成像(MRI)。由于spin-lattice relaxation time (T1)的缩短,GadoSpin M在T1-weighted MRI中增加了信号强度。静脉注射后,GadoSpinM迅速分布在细胞外空间。没有明显的血浆蛋白结合,同时在几小时内通过肾小球滤过(肾脏)排出稳定的复合物。Gd-DTPA不能穿透完整的血脑屏障,实际上用于脑肿瘤的临床诊断。

优点:

-涵盖全面,应用范围广;- 操作简单; - 高效。

数据:

图1.GD-DTPA的结构公式

组成成分:

▪850 µL GadoSpin™ M, MRI contrast agent (Gd-DTPA) or 5×850 µL GadoSpin™ M, MRI contrast agent (Gd-DTPA).

相关产品:

▪ExiTron V二聚化非离子胞外CT造影剂(货号#130-095-283)▪ExiTron P CT 肾排泄血管造影剂(货号#130-095-144)▪ExiTron nano 6000 肝脏显像CT 造影剂(货号#130-095-146)▪ExiTron nano 12000CT 血管造影剂(货号#130-095-698)▪GadoSpin F动脉粥样硬化成像剂MRI 造影剂(货号#130-095-162)▪GadoSpin P MR 血管造影剂(货号#130-095-136)▪GadoSpin D动态造影增强MRI 造影剂(货号#130-095-164)▪GadoSpin M 胞外MRI 造影剂(货号#130-095-134)▪FeraSpin R 肝脏显像MRI 造影剂(货号#130-095-138)▪FeraSpin XS 纳米微粒血管MRI 造影剂(货号#130-095-140)▪FeraSpin S 纳米微粒(货号#130-095-166)▪FeraSpin M纳米微粒血管MRI 造影剂(货号#130-095-168)▪FeraSpinL纳米微粒血管MRI 造影剂(货号#130-095-170)▪PolySon H超声微泡(货号#130-095-152)▪PolySon L hard-shell 超声微泡(货号#130-095-150)▪NiraWave C 光学显像造影剂(货号#130-095-154)▪NiraWave M 光学炎症显像造影剂(货号#130-095-157)▪NiraWave nano 780 光学血管造影剂(货号#130-095-693)
参考文献

1. Kiessling, F. et al. (2003) Dynamic T1-weighted monitoring of vascularization in human carcinoma heterotransplants by magnetic resonance imaging. Int. J. Cancer 104: 113-120

2. Furman-Haran, E. et al. (1996) Angiogenic response of MCF7 human breast cancer to hormonal treatment: assessment by dynamic GdDTPA-enhanced MRI at high spatial resolution. J. Magn. Reson. Imaging 6: 195-2023. Bjornaes, I. et al. (2000) Measurement of the extracellular volume of human melanoma xenografts by contrast enhanced magnetic resonance imaging. Magn. Reson. Imaging 18: 41-48

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