Rabbit anti Human histone H1.3 antibody 伯乐 VPA00783 HISTONE H1.3抗体

2024-10-28

Rabbit anti Human histone H1.3 antibody

货号:VPA00783

规格:100 µl

市场价格:3171

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:HISTONE H1.3

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human histone H1.3 antibodyrecognizes histone H1.3, also known as histone H1c, H1-3 and H1s-2. Histones are the major protein component of chromatin, with important roles in gene regulation. Histone H1 binds to linker DNA between nucleosomes, plays a role in higher-order chromatin stabilization, and is also able to fine-tune gene transcription in a locus-specific way (Brockers and Schneider, 2019). Histone variants replace canonical histones when nucleosomes are disrupted, with diverse implications for epigenetic gene regulation. Histone H1.3 is a histone variant and appears to have diverse roles in cancer. This protein has been suggested as a prognostic biomarker for pancreatic ductal adenocarcinoma (Bauden et al. 2017). Histone H1.3 has also been identified as a repressor for the oncogene H19, contributing to the suppression of epithelial ovarian carcinogenesis (Medrzycki et al. 2015).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography on immunogen.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3)2% Sucrose
ImmunogenSynthetic peptide directed towards the N terminal region of human histone H1.3
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
推荐产品
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (H/L):HRPSTAR208PWB2 ml

技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-49024.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价