Rabbit anti Human ataxin-1 antibody 伯乐人 VPA00865 ataxin-1 抗体-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human ataxin-1 antibody 伯乐人 VPA00865 ataxin-1 抗体

2024-10-28

Rabbit anti Human ataxin-1 antibody

货号：VPA00865

规格：100 µl

市场价格：2890

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原： ataxin-1

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human ataxin-1 antibodyrecognizes ataxin-1.The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for ATXN1 (provided by RefSeq, Jan 2010).Rabbit anti Human ataxin-1 antibody detects a band of 105 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide2% Sucrose
Immunogen	Recombinant protein of human ataxin-1
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型多克隆抗体

推荐用于 WB

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Rabbit anti Human ataxin-1 antibody 伯乐人 VPA00865 ataxin-1 抗体

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