Rabbit anti Human UBE3A antibody 伯乐 UBE3A 抗体人VPA00927-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human UBE3A antibody 伯乐 UBE3A 抗体人VPA00927

2024-10-28

Rabbit anti Human UBE3A antibody

货号：VPA00927

规格：100 µl

市场价格：2746

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：UBE3A

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human UBE3A antibodyrecognizes the UBE3A, also known as CTCL tumor antigen se37-2, E6AP ubiquitin-protein ligase, human papilloma virus E6-associated protein, renal carcinoma antigen NY-REN-54 and ubiquitin-protein ligase E3A.UBE3A encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of UBE3A causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of UBE3A results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined (provided by RefSeq, Jul 2008).Rabbit anti Human UBE3A antibody detects a band of 98 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	abbit polyclonal antibody purified by affinity chromatography on immunogen.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide<50% Glycerol
Immunogen	Recombinant protein of human UBE3A
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型多克隆抗体

推荐用于 WB

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Rabbit anti Human UBE3A antibody 伯乐 UBE3A 抗体 人VPA00927

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Rabbit anti Human UBE3A antibody 伯乐 UBE3A 抗体人VPA00927