Rabbit anti Human IL-12 receptor B2 antibody BIO-RAD VPA00729 Rabbit anti Human IL-12 receptor B2 antibody

2024-10-28

Rabbit anti Human IL-12 receptor B2 antibody

货号:VPA00729

规格:100μl

市场价格:4378

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:IL-12 receptor B2

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human IL-12 receptor B2 antibodyrecognizes interleukin-12 receptor subunit beta-2, also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2 or interleukin-12 receptor beta-2 chain.The protein encoded by IL12RB2 gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of IL12RB2 is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of IL12RB2 is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for IL12RB2 (provided by RefSeq, Apr 2012).Rabbit anti Human IL-12 receptor B2 antibody detects a band of 97 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionTRIS buffered glycine.
Preservative Stabilisers0.01% Thiomersal<50% Glycerol
ImmunogenRecombinant protein encompassing part of the middle region of human IL-12 receptor B2
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型 多克隆抗体

推荐用于 wb

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