Rabbit anti Human interleukin-21 antibody 伯乐 VPA00596 IL-21抗体

2024-10-28

Rabbit anti Human interleukin-21 antibody

货号:VPA00596

规格:100 µL

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:IL-21

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human interleukin-21 antibodyrecognizes interleukin-21 (IL-21), also known as Za11. IL-21 is a 133 amnio acid ~ 17 kDa immunoregulatory cytokine.The IL21 gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of IL21 plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Mutation of the IL21 gene causes Immunodeficiency, common variable, 11 (CVID11), a condition characterized by antibody and the inability to mount an antibody response to antigen leading to recurrent bacterial infections (Salzaret al.2014).Alternatively spliced transcript variants encoding multiple isoforms have been observed for IL21 (provided by RefSeq, Dec 2011).Rabbit anti Human interleukin-21 antibody detects a band of 17 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide2% Sucrose
ImmunogenSynthetic peptide directed towards the C-terminal region of Human interleukin-21
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

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