Rabbit anti Human MEK 2 antibody 伯乐 VPA00587 MEK 2抗体

2024-10-28

Rabbit anti Human MEK 2 antibody

货号:VPA00587

规格:100 µL

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:MEK 2

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human MEK 2 antibodyrecognizes MEK 2 also known as dual specificity mitogen-activated protein kinase kinase 2, also known as ERK activator kinase 2, MAP kinase kinase 2, MAPK/ERK kinase 2, MAPKK2 or p45.The protein encoded by MAP2K2 gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in MAP2K2 gene cause Cardiofaciocutaneous syndrome 4 (CFC4), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found inNoonan syndrome(Schulzet al.2008). The inhibition or degradation of this kinase is also found to be involved in the pathogenesis ofYersiniaand anthrax. A pseudogene, which is located on chromosome 7, has been identified for MAP2K2 (provided by RefSeq, Jul 2008).Rabbit anti Human MEK 2 antibody detects a band of 49 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide2% Sucrose
ImmunogenSynthetic peptide directed towards the N terminal region of human MEK 2
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

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