Rabbit anti Human PRPF8 antibody 伯乐 VPA00580 PRPF8抗体

2024-10-28

Rabbit anti Human PRPF8 antibody

货号:VPA00580

规格:100 µL

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:PRPF8

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human PRPF8 antibodyrecognizes PRPF8 also known as pre-mRNA-processing-splicing factor 8, 220 kDa U5 snRNP-specific protein, PRP8 homolog, PRP8 pre-mRNA processing factor 8 homolog, apoptosis-regulated protein 1, apoptosis-regulated protein 2, or splicing factor Prp8.Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by the PRPF8 gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein (provided by RefSeq, Jul 2008). Mutations in the PRPF8 gene cause development of Retinitis pigmentosa 13 (RP13) characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors (van Lith-Verhoevenet al.2002).Rabbit anti Human PRPF8 antibody detects a band of 250 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide2% Sucrose
ImmunogenSynthetic peptide directed towards the N terminal region of human PRPF8
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

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