Rabbit anti Human c-Myc antibody 伯乐 VPA00575 c-Myc抗体

2024-10-28

Rabbit anti Human c-Myc antibody

货号:VPA00575

规格:100 µL

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:c-Myc

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:其它

产品介绍
Rabbit anti Human c-Myc antibodyrecognizes c-Myc, also known as avian myelocytomatosis viral oncogene homolog, class E basic helix-loop-helix protein 39, myc-related translation/localization regulatory factor, transcription factor p64, v-myc myelocytomatosis viral oncogene homolog or proto-oncogene c-myc.The protein encoded by MYC gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of MYC have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma (BL). There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of MYC (provided by RefSeq, Jul 2008).Rabbit anti Human c-Myc antibody detects a band of 65 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide2% Sucrose
ImmunogenSynthetic peptide directed towards the N terminal region of human c-Myc
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

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