Rabbit anti Human HLA DRB1 antibody BIO-RAD VPA00683 Rabbit anti Human HLA DRB1 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human HLA DRB1 antibody BIO-RAD VPA00683 Rabbit anti Human HLA DRB1 antibody

2024-10-28

Rabbit anti Human HLA DRB1 antibody

货号：VPA00683

规格：100μl

市场价格：3800

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：HLA DRB1

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human HLA DRB1 antibodyrecognizes HLA class II histocompatibility antigen, DRB1-3 chain, also known as DR-1 beta chain, MHC class II HLA-DR beta 1 chain, MHC class II HLA-DR-beta cell surface glycoprotein, human leucocyte antigen DRB1 or lymphocyte antigen DRB1.The HLA-DRB1 gene belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9 (provided by RefSeq, Jul 2008).Rabbit anti Human HLA DRB1 antibody detects a band of 29 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution	Phosphate buffered saline.
Preservative Stabilisers	0.01% Thiomersal1% Bovine Serum Albumin<50% Glycerol
Immunogen	Recombinant protein encompassing part of the middle region of human HLA DRB1
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型多克隆抗体

推荐用于 wb

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Rabbit anti Human HLA DRB1 antibody BIO-RAD VPA00683 Rabbit anti Human HLA DRB1 antibody

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