Goat anti Human cortactin antibody 伯乐 CORTACTIN抗体 人 VPA00511

2024-10-28

Goat anti Human cortactin antibody

货号:VPA00511

规格:100 µl

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human cortactin antibodyrecognizes the Src substrate cortactin, also known as amplaxin or oncogene EMS1.The CTTN gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck (Patelet al.1996). The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. CTTN has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of CTTN contributes to tumor cell invasion and metastasis (Chumaet al.2004). Three splice variants that encode different isoforms have been identified for CTTN (provided by RefSeq, May 2010).Goat anti Human cortactin antibody detects a band of 80 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationGoat polyclonal antibody purified by affinity chromatography.
Buffer SolutionTRIS buffered saline.
Preservative Stabilisers0.09% Sodium Azide (NaN3)0.5% Bovine Serum Albumin.
ImmunogenPeptide sequence WKASAGHAVSIA-C
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
推荐产品
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (H/L):HRPSTAR208PWB2 ml

技术参数

产品应用 WB

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-49283.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价