Rabbit anti Human KDELR1 antibody 伯乐 KDELR1抗体人VPA00390-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human KDELR1 antibody 伯乐 KDELR1抗体人VPA00390

2024-10-28

Rabbit anti Human KDELR1 antibody

货号：VPA00390

规格：100 µl

市场价格：2890

产品类型：免疫组化一抗

品牌：Bio-Rad

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human KDELR1 antibodyrecognizes KDELR1, also known as ER lumen protein retention receptor 1 and putative MAPK-activating protein PM23.Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetra-peptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor is encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by the KDELR1 gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product (provided by RefSeq, Jul 2008).Rabbit anti Human KDELR1 antibody detects a band of 28 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution	Phosphate buffered saline.
Preservative Stabilisers	0.09% Sodium Azide (NaN3).
Immunogen	KLH-conjugated synthetic peptide corresponding to aa 185-211 of human KDELR1
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

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Rabbit anti Human KDELR1 antibody 伯乐 KDELR1抗体 人VPA00390

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Rabbit anti Human KDELR1 antibody 伯乐 KDELR1抗体人VPA00390