Rabbit anti Human RPS3 antibody 伯乐 RPS3 抗体 人PA00367

2024-10-28

Rabbit anti Human RPS3 antibody

货号:VPA00367

规格:100 µl

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human RPS3 antibodyrecognizes RPS3, also known as 40S ribosomal protein S3 and IMR-90 ribosomal protein S3.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. The RPS3 gene encodes a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. RPS3 belongs to the S3P family of ribosomal proteins. mouse and rat RPS3 have an extra-ribosomal role as an endonuclease involved in the repair of UV-induced DNA damage. RPS3 appears to be located in both the cytoplasm and nucleus but not in the nucleolus. Higher levels of expression of RPS3 in colon adenocarcinomas and adenomatous polyps compared to adjacent normal colonic mucosa have been observed. RPS3 is co-transcribed with the small nucleolar RNA genes U15A and U15B, located in its first and fifth introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of RPS3 dispersed through the genome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for RPS3 (provided by RefSeq, May 2012).Rabbit anti Human RPS3 antibody detects a band of 27 kDa and has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide (NaN3)2% Sucrose
ImmunogenSynthetic peptide corresponding to the C-terminal region of human RPS3
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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