Rabbit anti Human PRMT1 antibody BIO-RAD VPA00236 PRMT1 antibody

2024-10-28

Rabbit anti Human PRMT1 antibody

货号:VPA00236

规格:100μl

市场价格:2916

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:PRMT1

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human PRMT1 antibodyrecognizes protein arginine N-methyltransferase 1, also known as HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2, heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2, histone-arginine N-methyltransferase and interferon receptor 1-bound protein 4.Encoded by the PRMT1 gene, protein arginine N-methyltransferase 1 is a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of PRMT1 may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PRMT1, and a pseudogene of PRMT1 is located on the long arm of chromosome 5 (provided by RefSeq, Dec 2011).Rabbit anti Human PRMT1 antibody detects a band of 42 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit Ig fraction prepared by ammonium sulphate precipitation.
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenKLH conjugated synthetic peptide between 317-346 amino acids from the C-terminal region of human PRMT1
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型 多克隆抗体

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