Goat anti Human IRF4 antibody 伯乐 IRF4 抗体 人VPA00156

2024-10-28

Goat anti Human IRF4 antibody

货号:VPA00156

规格:100 µl

市场价格:3613

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human IRF4 antibodyrecognizes Interferon regulatory factor 4 (IRF4), also known as Lymphocyte-specific interferon regulatory factor (LSIRF), multiple myeloma oncogene 1 and NF-EM5.IRF4 belongs to the interferon regulatory factor family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving IRF4 and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for IRF4 (provided by RefSeq, Aug 2010).Goat anti Human IRF4 antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationGoat polyclonal antibody purified by affinity chromatography.
Buffer SolutionTRIS buffered saline.
Preservative Stabilisers0.02% Sodium Azide (NaN3) 0.5 % BSA
ImmunogenPeptide with the sequence C-HISNPEDYHRSIR, from the C terminus of the protein sequence
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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