Rabbit anti Human NEDD4L antibody 伯乐 VPA00322 NEDD4L抗体

2024-10-28

Rabbit anti Human NEDD4L antibody

货号:VPA00322

规格:100 uL

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:NEDD4L

物种:人

宿主:兔

抗体亚型:IgG

荧光染料:Purified

产品介绍
Rabbit anti Human NEDD4L antibodyrecognizes NEDD4L, also known as E3 ubiquitin ligase NEDD4-like and ubiquitin-protein ligase Rsp5.The NEDD4L gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The NEDD4L protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in NEDD4L may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for NEDD4L (provided by RefSeq, Mar 2012).Rabbit anti Human NEDD4L antibody detects a band of 135 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationRabbit polyclonal antibody purified by affinity chromatography
Buffer SolutionPhosphate buffered saline.
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenKLH-conjugated synthetic peptide corresponding to aa 576-604 of human NEDD4L
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
推荐产品
DescriptionProduct CodeApplicationsPack Size
Goat anti Rabbit IgG (H/L):HRPSTAR208PWB2 ml

技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

推荐用于 WB

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价,请加客服QQ:1749072012 、客服微信:jinshanbio,或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务,数据资源基于CC协议。
© 本文地址:https://gibcohyclone.cn/thread-49584.htm
产品询价需求提交
返回
扫码添加客服微信,咨询产品报价