Rabbit anti PDCD4 伯乐VPA00093 PDCD4 抗体 WB-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti PDCD4 伯乐VPA00093 PDCD4 抗体 WB

2024-10-28

Rabbit anti PDCD4

货号：VPA00093

规格：100 µl

市场价格：2890

产品类型：免疫组化一抗

品牌：Bio-Rad

物种：人/小鼠/大鼠

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human PDCD4 antibodyrecognizes programmed cell death 4 (PDCD4), a novel tumor suppressor.PDCD4 interacts with the RNA helicase eIF4A and the scaffolding protein eIF4G, two components of the translation initiation complex, and thus inhibits protein synthesis (Yanget al.2003). PDCD4 has also been shown to inhibit transcription factor activator protein-1 (AP-1), which regulates several events required for cell invasion, including expression of matrix metalloproteinases and cell motility (Wanget al.2013).PDCD4 localizes to the nucleus in proliferating cells, and its expression is modulated by cytokines in natural killer and T-cells. PDCD4 expression is down regulated with tumor progression in carcinomas of the lung, colon, prostate and breast.Rabbit anti Human PDCD4 antibody detects programmed cell death 4 as a single band of 52 kDa in a wide range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	100μl Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution	TRIS buffered saline.
Preservative Stabilisers	0.09% Sodium Azide (NaN3).
Immunogen	Synthetic peptide corresponding to amino acids near the C-terminal of human PDCD4
Approx. Protein Concentrations	IgG concentration 0.5 mg/ml.
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

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Rabbit anti PDCD4 伯乐VPA00093 PDCD4 抗体 WB

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