goat anti CRTC2 伯乐 CRTC2 抗体 人VPA00131

2024-10-28

goat anti CRTC2

货号:VPA00131

规格:100 µl

市场价格:3171

产品类型:免疫组化一抗

品牌:Bio-Rad

物种:人/小鼠/大鼠

宿主:山羊

抗体亚型:IgG

荧光染料:Purified

产品介绍
Goat anti Human CRTC2 antibodyrecognizes the CREB-regulated transcription coactivator 2, also known as transducer of regulated cAMP response element-binding protein 2 (TORC-2) or transducer of CREB protein 2.CRTC2 is a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions CRTC2 is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, CRTC2 translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in the CRTC2 gene may increase the risk of type 2 diabetes. A pseudogene of CRTC2 is located on the long arm of chromosome 5 (provided by RefSeq, Dec 2010).Goat anti Human CRTC2 antibody detects a band of 80 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationGoat polyclonal antibody purified by affinity chromatography.
Buffer SolutionTRIS buffered saline.
Preservative Stabilisers0.02% Sodium Azide (NaN3) 0.5% BSA
ImmunogenPeptide with the sequence C-DPAVEDSFRSDRLQ, from the C Terminus of the protein sequence
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

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