VEGF Receptor 2 Polyclonal Antibody

货号：PA5-16487

规格：500 µL

价格：5831

产品类型：免疫组化一抗

品牌：Thermo Fisher

物种：大鼠

宿主：兔

抗体亚型：IgG

荧光染料：其它

类型:	单抗	同型对照：
浓度：	1 mg/mL	用法：	5-10 µg/mL (WB)；1:50(IHC (P))

产品详细信息PA5-16487 targets Flk-1 in IHC (P) and WB applications and shows reactivity with mouse, Rat, and Human samples.The PA5-16487 immunogen is a synthetic peptide from C-terminus of the precursor form of the mouse Flk-1.靶标信息Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.

数据

VEGF Receptor 2 Antibody (PA5-16487) in IHCFormalin-fixed, paraffin-embedded human angiosarcoma stained with Flk-1/ VEGFR2 antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.

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参考文献：

1.Oncology lettersMyoferlin expression in non-small cell lung cancer: Prognostic role and correlation with VEGFR-2 expression."PA5-16487 was used in immunohistochemistry - paraffin section and western blot to characterize the prognostic role of myoferlin expression in non-small cell lung cancer in correlation with VEGFR-2 expression"2.Scientific reportsHypoxia and proangiogenic proteins in human ameloblastoma."PA5-16487 was used in Immunohistochemistry to investigate the expression of the HIF-1α, MMP-2, VEGF, and VEGFR-2 proteins among 24 ameloblastoma cases, 10 calcifying odontogenic cysts, and 9 dental follicles by immunohistochemistry."3.Annals of oncology : official journal of the European Society for Medical OncologyA phase II study of tivozanib in patients with metastatic and nonresectable soft-tissue sarcomas."PA516487 was used in immunohistochemistry to evaluate the use of Tivozanib to treat patients with soft tissue sarcomas"4.Oncology lettersMyoferlin expression in non-small cell lung cancer: Prognostic role and correlation with VEGFR-2 expression."PA5-16487 was used in immunohistochemistry - paraffin section and western blot to characterize the prognostic role of myoferlin expression in non-small cell lung cancer in correlation with VEGFR-2 expression"

技术参数

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