Rabbit anti Human disabled homolog 2 antibody BIO-RAD VPA00208 Rabbit anti Human disabled homolog 2 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti Human disabled homolog 2 antibody BIO-RAD VPA00208 Rabbit anti Human disabled homolog 2 antibody

2024-10-28

Rabbit anti Human disabled homolog 2 antibody

货号：VPA00208

规格：100μl

市场价格：2916

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：disabled homolog 2

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human disabled homolog 2 antibodyrecognizes disabled homolog 2, also known as differentially-expressed protein 2 and mitogen-responsive phosphoprotein.Encoded by the DAB2 gene, disabled homolog 2 is a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for DAB2 (provided by RefSeq, Oct 2011).Rabbit anti Human disabled homolog 2 antibody detects a band of 96 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution	Phosphate buffered saline.
Preservative Stabilisers	0.09% Sodium Azide (NaN3).
Immunogen	KLH conjugated synthetic peptide between 743-770 amino acids from the C-terminal region of human disabled homolog 2
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型多克隆抗体

推荐用于 wb

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Rabbit anti Human disabled homolog 2 antibody BIO-RAD VPA00208 Rabbit anti Human disabled homolog 2 antibody

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