Rabbit anti MCM6 伯乐 MCM6抗体 VPA00023-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Rabbit anti MCM6 伯乐 MCM6抗体 VPA00023

2024-10-28

Rabbit anti MCM6

货号：VPA00023

规格：100 µl

市场价格：5202

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：MCM6

物种：人

宿主：兔

抗体亚型：IgG

荧光染料：Purified

产品介绍
Rabbit anti Human MCM6 antibodyrecognizes human minichromosome maintenance 6 (MCM6), also known as DNA replication licensing factor or p105MCM. MCM6 is a 821 amino acid nuclear component of the MCM complex containing a singleMCMdomain.MCM6 is involved in the initiation and control of eukaryotic DNA replication. MCM6 forms a hexameric protein complex with MCM4 and 7, which has DNA helicase activity and may act as a DNA unwinding enzyme (Kanteret al.2008). The phosphorylation of this complex by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex (Ishimiet al.2001). MCM6 has been noted to have elevated expression in Hodgkin's lymphoma (Karimiet al.2008) and be a predictor of survival in patients with mantle cell lymphoma (Schraderet al.2005).Rabbit anti Human MCM6 antibody recognizes human MCM6 as a single band of ~105 kDa in multiple human cell line lysates by western blotting under reducing conditions. It also cross reacts with rodent cell lines tested.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution	TRIS buffered saline.
Preservative Stabilisers	0.09% Sodium Azide (NaN3).
Immunogen	Synthetic peptide corresponding to a region within human MCM6
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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技术参数

产品应用 WB

产品类型 PrecisionAb Polyclonal

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Rabbit anti MCM6 伯乐 MCM6抗体 VPA00023

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