Mouse anti Plc GAMMA-1 BIO-RAD VMA00584 PLC gamma-1 antibody

2024-10-28

Mouse anti Plc GAMMA-1

货号:VMA00584

规格:100μl

市场价格:3205

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:PLC gamma-1

物种:人

宿主:小鼠

抗体亚型:IgG2a

克隆号: 1F1

荧光染料:Purified

产品介绍
Mouse anti Human PLC gamma-1 antibodyrecognizes the 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, also known as PLC-148, phosphatidylinositol phospholipase C or phosphoinositidase C.The protein encoded by PLCG1 gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for PLCG1 (provided by RefSeq, Jul 2008).Mouse anti Human PLC gamma-1 antibody detects a band of 150 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody purified by affinity chromatography on Protein G from ascites.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin<50% Glycerol
ImmunogenE. coli-derived recombinant human PLC gamma-1
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型 多克隆抗体

推荐用于 wb

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