Mouse anti Human TAB1 antibody BIO-RAD VMA00576 TAB1 antibody-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human TAB1 antibody BIO-RAD VMA00576 TAB1 antibody

2024-10-28

Mouse anti Human TAB1 antibody

货号：VMA00576

规格：100μl

市场价格：2916

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：TAB1

物种：人

宿主：小鼠

抗体亚型：IgG2a

荧光染料：Purified

产品介绍
Mouse anti Human TAB1 antibodyrecognizes the TGF-beta-activated kinase 1 and MAP3K7-binding protein 1, also known as TAK1-binding protein 1, mitogen-activated protein kinase kinase kinase 7-interacting protein 1 or transforming growth factor beta-activated kinase-binding protein 1.The protein encoded by TAB1 gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha). Alternatively spliced transcript variants encoding distinct isoforms have been reported (provided by RefSeq, Jul 2008).Mouse anti Human TAB1 antibody detects a band of 60 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Mouse monoclonal antibody purified by affinity chromatography on Protein G from ascites.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin<50% Glycerol
Immunogen	E. coli-derived recombinant human TAB1 (amino acids 1 - 300)
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√	1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型多克隆抗体

推荐用于 wb

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Mouse anti Human TAB1 antibody BIO-RAD VMA00576 TAB1 antibody

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