Mouse anti Human CD104 antibody BIO-RAD VMA00285 Mouse anti Human CD104 antibody

2024-10-28

Mouse anti Human CD104 antibody

货号:VMA00285

规格:100μl

市场价格:2890

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:CD104

物种:人

宿主:小鼠

抗体亚型:IgG1

荧光染料:Purified

产品介绍
Mouse anti Human CD104 antibodyrecognizes the CD104 antigen, also known as integrin beta-4, integrin beta-4 subunit and GP150.Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. Encoded by the ITGB4 gene, integrin beta 4 subunit is a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in ITGB4 gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for ITGB4 (provided by RefSeq, Jul 2008).Mouse anti Human CD104 antibody detects a band of 210 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationMouse monoclonal antibody prepared by affinity chromatography on Protein G from ascites.
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09% Sodium Azide (NaN3).
ImmunogenRecombinant protein corresponding to amino acids 1619-1822 of human CD104 expressed inE. coli
AcknowledgementsPrecisionAb is a trademark of Bio-Rad Laboratories.
RegulatoryFor research purposes only
Guarantee12 months from date of despatch.
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application NameVerifiedMin DilutionMax Dilution
Western Blotting1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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产品应用 wb

产品类型 单克隆抗体

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