Mouse anti Human poly (ADP-ribose) polymerase 1 antibody BIO-RAD VMA00016 Mouse anti Human poly (ADP-ribose) polymerase 1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human poly (ADP-ribose) polymerase 1 antibody BIO-RAD VMA00016 Mouse anti Human poly (ADP-ribose) polymerase 1

2024-10-28

Mouse anti Human poly (ADP-ribose) polymerase 1 antibody

货号：VMA00016

规格：100μl

市场价格：2916

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：poly (ADP-ribose) polymerase 1

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：A6.4.12

荧光染料：Purified

产品介绍
Mouse anti Human poly (ADP-ribose) polymerase 1 antibodyrecognizes poly (ADP-ribose) polymerase 1 (PARP-1), a nuclear enzyme cleaved during apoptosis (Soldaniet al.2002).PARP-1 is a caretaker enzyme involved in DNA damage repair (Langelieret al.2013). It plays roles in diabetes pathophysiology (Andreoneet al.2012) and tumor proliferation (Rosadoet al2013). As well as protecting cells from genomic instability, PARP-1 is also involved in the development of both inflammatory and immune responses, and cell death by apoptosis and necrosis (Erdélyiet al.2005).PARP-1 represents a promising target for new developments in therapeutic treatment of immune mediated diseases (Rosadoet al.2013) and has considerable potential for delivering selective tumor cell killing while sparing normal cells (Pintonet al.2013).Mouse anti Human poly (ADP-ribose) polymerase 1 antibody recognizes PARP-1 as a single band of ~116 kDa in western blotting in multiple cell line lysates including myeloid, lymphoid, neuronal, adenocarcinoma, sarcoma and embryonic kidney.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Mouse monoclonal antibody purified by affinity chromatography on Protein A from tissue culture supernatant.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)
Immunogen	Human PARP-1
Acknowledgements	PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
应用
Application Name	Verified	Min Dilution	Max Dilution
Western Blotting	√		1/1000
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.Flow CytometryUse 10ul of the suggested working dilution to label 106cells or 100ul human whole blood.
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技术参数

产品应用 wb

产品类型单克隆抗体

推荐用于 wb

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Mouse anti Human poly (ADP-ribose) polymerase 1 antibody BIO-RAD VMA00016 Mouse anti Human poly (ADP-ribose) polymerase 1

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