Mouse anti human CD45RA:StarBright Blue 700

货号：MCA88SBB700

规格：100 Tests/0.5mL

市场价格：3553

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD45RA

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：F8-11-13

荧光染料：StarBright Blue 700

类型:	单抗	同型对照：	IgG1
浓度：		用法：	5 µL/test(Flow)
免疫原性：	Human T lymphocytes

Mouse anti Human CD45RA antibody, clone F8-11-13recognizes the human CD45RA cell surface antigen.CD45 is a complex molecule existing in a number of isoforms. Antibodies recognizing a common epitope on all of these isoforms are termed CD45 whilst those recognizing only individual isoforms are termed CD45RA or CD45RO etc.Mouse anti Human CD45RA antibody, clone F8-11-13 reacts with the high molecular weight form of the leucocyte common antigen (LCA) expressed by B lymphocytes and a subset of T lymphocytes.Mouse anti Human CD45RA antibody, clone F8-11-13 is routinely tested in flow cytometry on human peripheral blood lymphocytes.

数据

Figure A. StarBright Blue 700 conjugated Mouse anti Human CD45RA (MCA88SBB700). Figure B. StarBright Blue 700 conjugated Mouse anti Human CD45RA (MCA88SBB700) and StarBright Violet 440 conjugated Mouse anti Human CD45RO (MCA461SBV440). All experiments performed on red cell lysed human blood gated on live single lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.

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参考文献：

1. Dalchau, R. & Fabre, J.W. (1981) Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. Evidence for structural and possible functional diversity of the human leukocyte common molecule.J Exp Med. 153 (4): 753-65.2. O'Grady, J.T.et al.(1994) CD40 expression in Hodgkin's disease.Am J Pathol. 144 (1): 21-6.3. Franitza, S.et al.(2002) TGF-beta1 enhances SDF-1alpha-induced chemotaxis and homing of naive T cells by up-regulating CXCR4 expression and downstream cytoskeletal effector molecules.Eur J Immunol. 32 (1): 193-202.4. Leigh, J.E.et al.(2006) Characterization of the immune status of CD8+ T cells in oral lesions of human immunodeficiency virus-infected persons with oropharyngeal Candidiasis.Clin Vaccine Immunol. 13 (6): 678-83.5. Hunt, L.et al.(2016) T cell subsets: an immunological biomarker to predict progression to clinical arthritis in ACPA-positive individuals.Ann Rheum Dis. 75 (10): 1884-9.6. Ibana, J.A.et al.(2012) The major CD8 T cell effector memory subset in the normal andChlamydia trachomatis-infected human endocervix is low in perforin.BMC Immunol. 13: 66.7. Ponchel, F.et al.(2014) An immunological biomarker to predict MTX response in early RA.Ann Rheum Dis. 73 (11): 2047-53.

技术参数

产品应用 Flow

产品类型 单克隆抗体

推荐用于 Flow

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