Mouse anti Pig CD335 antibody, clone VIV-KM1 BIO-RAD MCA5972A488 Mouse anti Pig CD335 antibody, clone VIV-KM1-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Pig CD335 antibody, clone VIV-KM1 BIO-RAD MCA5972A488 Mouse anti Pig CD335 antibody, clone VIV-KM1

2024-10-29

Mouse anti Pig CD335 antibody, clone VIV-KM1

货号：MCA5972A488

规格：100 Tests/1ml

市场价格：4165

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD335

物种：pig

宿主：小鼠

抗体亚型：IgG1

克隆号：100 Tests

荧光染料：Alexa Fluor 488

产品介绍
Mouse anti Pig CD335 antibody, clone VIV-KM1recognizes the porcine homologue of human CD335, also known as NKp46 and natural cytotoxicity triggering receptor 1 (NCR1), a member of the natural cytotoxicity receptor (NCR) family.CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor and is involved in the control of viral infection and tumor development. CD335 is expressed by human natural killer cells (Sivoriet al.1997). The development of monoclonal antibodies to bovine CD335 (cloneAKS1) (Storsetet al.2004) and ovine CD335 (cloneEC1.1) (Connelleyet al.2011) have enabled researchers to identify and better understand ruminant NK cells.Mouse anti Pig CD335 antibody, clone VIV-KM is the first monoclonal developed to specifically identify porcine CD335 and provides a reagent to facilitate a better understanding of the pig immune system and aid in the understanding of the role of NK cells in host pathogen defense. Porcine CD335 is not expressed by all NK cells and expression may be influenced by cytokine production (Mairet al.2012).
产品详情
Target Species	Pig
Product Form	Purified IgG conjugated to Alexa Fluor® 488 - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin
Fusion Partners	Fusion protein consisting of the extracellular region of porcine CD335
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
Alexa Fluor®488	495	519
Acknowledgements	This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchased product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Hogg, N. & Horton, M.A. (1987) Myeloid antigens: new and previously defined clustersin Leucocyte Typing III White Cell differentiation antigens. Edited by McMichael, A.J.,et al.2.Yoshino, N.et al.(2000) Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies.Exp Anim. 49 (2): 97-110.3.Jonker, M.et al. (1989) Reactivity of mAb specific for human CD markers with Rhesus monkey leucocytes.Leucocyte Typing IV. Oxford University Press p 1058-63.4.Hogg, N.et al.(1984) Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.Immunology. 53 (4): 753-67.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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Mouse anti Pig CD335 antibody, clone VIV-KM1 BIO-RAD MCA5972A488 Mouse anti Pig CD335 antibody, clone VIV-KM1

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