Mouse anti Human osteoprotegerin, clone E01-10F11 BIO-RAD MCA5970GA Mouse anti Human osteoprotegerin, clone E01-10F11-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human osteoprotegerin, clone E01-10F11 BIO-RAD MCA5970GA Mouse anti Human osteoprotegerin, clone E01-10F11

2024-10-29

Mouse anti Human osteoprotegerin, clone E01-10F11

货号：MCA5970GA

规格：0.1 mg

市场价格：2550

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：osteoprotegerin

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：E01-10F11

荧光染料：Purified

产品介绍
Mouse anti Human osteoprotegerin, clone E01-10F11, recognizes osteoprotegerin (OPG), a cytokine receptor and member of the tumour necrosis factor (TNF) receptor superfamily. The role of OPG involves it acting as a decoy receptor for the ligand of CD254 and thereby preventing its function in osteoclastogenesis. In addition to this it may act as a decoy receptor for TNF related apoptosis inducing ligand (TRAIL) (Emeryet al.1998andSchoppetet al.2002). The combination of these two roles allows OPG to inhibit NFkB’s regulatory effects on inflammation, skeletal, and vascular systems.OPG is highly expressed in a wide range of tissues, including adult heart, lung, liver, prostate, ovary and bone marrow. More recently a role for OPG in cardiovascular disease has emerged and it is now clinically relevant biomarker of vascular health (Bierre, 2013).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein G from ascites
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Carrier Free	Yes
Immunogen	E. coliderived recombinant protein corresponding to aa 22-201 of human osteoprotegerin
Fusion Partners	Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line
Approx. Protein Concentrations	IgG concentration 1.0 mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at -20℃ only.This product should be stored undiluted.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/50
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Emery, J.G.et al.(1998) Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.J Biol Chem. 273 (23): 14363-7.2.Schoppet, M.et al.(2004) Localization of osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand, and receptor activator of nuclear factor-kappaB ligand in Mönckeberg's sclerosis and atherosclerosis.J Clin Endocrinol Metab. 89 (8): 4104-12.3.Bjerre, M. (2013) Osteoprotegerin (OPG) as a biomarker for diabetic cardiovascular complications.Springerplus. 2: 658.

技术参数

产品应用 Elisa；WB

产品类型 Monoclonal Antibody

推荐用于 Elisa；WB

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Mouse anti Human osteoprotegerin, clone E01-10F11 BIO-RAD MCA5970GA Mouse anti Human osteoprotegerin, clone E01-10F11

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