Mouse anti Rat CD11b, clone OX-42 BIO-RAD MCA275A647 Mouse anti Rat CD11b, clone OX-42-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Rat CD11b, clone OX-42 BIO-RAD MCA275A647 Mouse anti Rat CD11b, clone OX-42

2024-10-29

Mouse anti Rat CD11b, clone OX-42

货号：MCA275A647

规格：100 Tests/1ml

市场价格：3956

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD11b

物种：大鼠

宿主：小鼠

抗体亚型：IgG2a

克隆号：OX-42

荧光染料：Alexa Fluor 647

产品介绍
Mouse anti Rat CD11b, clone OX-42recognizes rat CD11b, also known asintegrin alpha-M, the receptor for the iC3b component of complement. CD11b is a 1151 amino acid single pass type 1 transmembrane glycoprotein posessing a singlevWFAdomain and multipleFG-GAPrepeats. CD11b is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35% of alveolar macrophages. The antibody also labels dendritic cells, granulocytes andmicrogliain the brain (Robinsonet al.1986).Mouse anti Rat CD11b, clone OX-42 is reported to inhibit complement mediated rosettes (Robinsonet al.1986) as well as inhibit myelin binding and uptake (van der Laanet al.1996).
产品详情
Target Species	Rat
Product Form	Purified IgG conjugated to Alexa Fluor®647- liquid
Preparation	Purified IgG prepared by affinity chromatography on protein G from tissue culture supernatant.
Buffer Solution	Phosphate buffered saline
Fusion Partners	Spleen cells from immunised BALB/c mice were fused with cells of the NSO/U mouse myeloma cell line.
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1%Bovine Serum Albumin
Approx. Protein Concentrations	IgG concentration 0.05 mg/ml
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
Alexa Fluor®647	650	665
Acknowledgements	This product is provided under an intellectual property licence from Life Technologies Corporation. The transfer of this product is contingent on the buyer using the purchase product solely in research, excluding contract research or any fee for service research, and the buyer must not sell or otherwise transfer this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; (c) manufacturing or quality assurance or quality control, or (d) resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad CA 92008 USA or outlicensing@thermofisher.com
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat	1/10
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
二抗
Description	Product Code	Applications	Pack Size
Mouse IgG2a Negative Control:Alexa Fluor® 647	MCA1210A647	F	100 Tests/1ml
文献
1.Stidworthy, M.F.et al.(2004) Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination.Brain, 127: 1928-41.2.Baca Jones, C.C. (2009) Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells.Virology. 388: 78-90.3.Clark, A.K.et al(2007) Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain.Proc Natl Acad Sci U S A. 104: 10655-60.4.Draskovic-Pavlovic, B.et al.(1999) Differential effects of anti-rat CD11b monoclonal antibodies on granulocyte adhesiveness.Immunology. 96: 83-9.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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Mouse anti Rat CD11b, clone OX-42 BIO-RAD MCA275A647 Mouse anti Rat CD11b, clone OX-42

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