Mouse anti Human CD154 (Soluble) antibody, clone 1H4 BIO-RAD MCA2755 Mouse anti Human CD154 (Soluble) antibody, clone 1H4-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human CD154 (Soluble) antibody, clone 1H4 BIO-RAD MCA2755 Mouse anti Human CD154 (Soluble) antibody, clone 1H4

2024-10-29

Mouse anti Human CD154 (Soluble) antibody, clone 1H4

货号：MCA2755

规格：0.2 mg

市场价格：3375

产品类型：免疫组化一抗

品牌：Bio-Rad

抗原：CD154 (Soluble)

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：1H4

荧光染料：Purified

产品介绍
Mouse anti Human CD154 (Soluble) antibody, clone 1H4recognizes the soluble form of CD154, otherwise known as CD40 Ligand/TRAP, a ~32 kDa glycoprotein and member of the TNF family, which is specifically expressed on activated, but not resting, CD4+ T cells, dendritic cells (DCs), B cells and macrophages.CD154 binds CD40, and acts as a key co-stimulatory molecule through the activation of antigen-presenting cells, and as a regulator of the generation and functional properties of Th1 helper cells. CD154 exists in both a membrane-bound and soluble form, the latter of which is generated through proteolytic processing by a matrix metalloproteinase (MMP), in activated cells.The binding of CD154 with its receptor CD40 is vital for many biological processes, including Ig class switching, germinal centre formation and the survival of CD40+ B cells, B cell proliferation in the absence of co-stimulus, the production of IgE in the presence of interleukin-4 (IL-4), and also in the production of pro-inflammatory cytokines, MMPs, prostaglandins and adhesion molecule upregulation, in non-immune cells.Mouse anti Human CD154 (Soluble) antibody, clone 1H4 recognizes the soluble form of the protein.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer Solution	Phosphate buffered saline
Immunogen	Recombinant human soluble CD154 conjugated to BSA.
Fusion Partners	Spleen cells from immunised Balb/c mice were fused with cells of the myeloma Sp2/0 cell line.
Preservative Stabilisers	<0.1% Sodium Azide (NaN3)
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	1/50
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
推荐产品
Description	Product Code	Applications	Pack Size
Goat anti Mouse IgG (H/L):Alk. Phos. (Multi Species Adsorbed)	STAR117A	F	0.5mg
文献
1.Pietravalle, F.et al.(1996) Human native soluble CD40L is a biologically active trimer, processed inside microsomes.J Biol Chem. 271 (11): 5965-7.

技术参数

产品应用 Elisa;WB

产品类型 Monoclonal Antibody

推荐用于 Elisa;WB

© bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪是专业的授权总代理区域代理经销平台。
© 如需询价，请加客服QQ：1749072012 、客服微信：jinshanbio，或发送邮件到1749072012@qq.com
© 平台为生命科学研究相关领域提供一站式耗材试剂仪器解决方案和采购服务，数据资源基于CC协议。
© 本文地址：https://gibcohyclone.cn/thread-52460.htm

特别声明：以上内容(如有图片亦包括在内)来源于授权厂家或网络，如有侵权，请联系删除，本平台不提供信息存储服务。

Notice: The content above (including the pictures if any)comes from authorized manufacturers or networks. In case of infringement, please contact to delete it. This platform does not provide information storage services.

产品询价需求提交

Mouse anti Human CD154 (Soluble) antibody, clone 1H4 BIO-RAD MCA2755 Mouse anti Human CD154 (Soluble) antibody, clone 1H4

相关推荐