mouse anti human FACTOR P 伯乐 mouse anti human FACTOR P MCA2618

2024-10-29

mouse anti human FACTOR P

货号:MCA2618

规格:0.1 mg

市场价格:6401

产品类型:免疫组化一抗

品牌:Bio-Rad

抗原:Complement Factor P

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:062-260 (10-24)

荧光染料:Purified

产品介绍
Mouse anti Human complement factor P antibody, clone 062-260 (10-24)recognises human complement factor P, a 53 kDa glycosylated protein present in serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.Mouse anti Human complement factor P antibody, clone 10-24 does not inhibit function of complement factor P.
产品详情
Target SpeciesHuman
Product FormPurified Ig - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from ascites
Buffer SolutionBorate buffered saline
ImmunogenPurified Human factor P from human serum.
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
Preservative Stabilisers0.09% Sodium Azide (NaN3)
RegulatoryFor research purposes only
GuaranteeGuaranteed until date of expiry. Please see product label.
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Hourcade, D.E. (2006) The role of properdin in the assembly of the alternative pathway C3 convertases of complement.J Biol Chem. 281 (4): 2128-32.2.Jelezarova, E.et al.(2000) Interaction of C3b(2)--IgG complexes with complement proteins properdin, factor B and factor H: implications for amplification.Biochem J. 349 (Pt 1): 217-23

技术参数

产品应用 IHC(F);WB;ELISA

产品类型 单克隆抗体

推荐用于 IHC(F);WB;ELISA

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