Mouse anti Human Factor P 伯乐 Mouse anti Human Factor P MCA2617

2024-10-29

Mouse anti Human Factor P

货号:MCA2617

规格:0.1 mg

市场价格:5925

产品类型:流式抗体

品牌:Bio-Rad

抗原:Factor P

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:062-27.8.1 (10-18)

荧光染料:Purified

产品介绍
Mouse anti Human Factor P antibody, clone 062-27.8.1 (10-18)recognizes human factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly toNeisseriaspecies and meningococcal infections.Mouse anti Human Factor P antibody, clone 10-18 is reported to inhibit the function of factor P. Removal of sodium azide is recommended prior to use in functional assays.
产品详情
Target SpeciesHuman
Product FormPurified Ig - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from ascites
Buffer SolutionBorate buffered saline
ImmunogenNative purified factor P from human serum.
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
Preservative Stabilisers0.1%Sodium Azide (NaN3)
RegulatoryFor research purposes only
GuaranteeGuaranteed until date of expiry. Please see product label.
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Hourcade, D.E. (2006) The role of properdin in the assembly of the alternative pathway C3 convertases of complement.J Biol Chem. 281 (4): 2128-32.2.Jelezarova, E.et al.(2000) Interaction of C3b(2)--IgG complexes with complement proteins properdin, factor B and factor H: implications for amplification.Biochem J. 349 (Pt 1): 217-23

技术参数

产品应用 Flow;IHC(F);WB;ELISA;FN

产品类型 单克隆抗体

推荐用于 Flow;IHC(F);WB;ELISA;FN

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