mouse anti human C3c 伯乐 mouse anti human C3c-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

mouse anti human C3c 伯乐 mouse anti human C3c

2024-10-29

mouse anti human C3c

货号：MCA2605

规格：0.1 mg

市场价格：5925

产品类型：流式抗体

品牌：Bio-Rad

抗原：C3c

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：013E-498.2.3 (10-02A)

荧光染料：Purified

产品介绍
Mouse anti human C3c, clone 013E-498.2.3 (10-02A),recognizes the ~135 kDa complement component 3c present in serum. C3c is generated over the course of complement activation, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a. C3b is further degraded into iC3b and C3dg/C3d. iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha' chain fragment 1 + alpha' chain fragment 2), C3dg and C3f.C3 is crucial in the induction of tolerance generated when an antigen is introduced into immunoprivileged sites and this is exploited by pathogens and cancer cells to evade the immune system by inhibiting complement activation.
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution	Borate buffered saline
Immunogen	Human C3 from normal serum, highly purified by chromatography.
Approx. Protein Concentrations	Current, batch-specific concentration 1.2 mg/ml
Preservative Stabilisers	0.1% Sodium Azide (NaN3)
Regulatory	For research purposes only
Guarantee	Guaranteed until date of expiry. Please see product label.
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
推荐产品
Description	Product Code	Applications	Pack Size
Mouse IgG1 Negative Control	MCA928	F	100 Tests/1ml
文献
1.Sica, M.et al.(2017) Eculizumab treatment: stochastic occurrence of C3 binding to individual PNH erythrocytes.J Hematol Oncol. 10 (1): 126.

技术参数

产品应用 Flow;IHC(F);WB;ELISA

产品类型单克隆抗体

推荐用于 Flow;IHC(F);WB;ELISA

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mouse anti human C3c 伯乐 mouse anti human C3c

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