mouse anti human C1q 伯乐 mouse anti human C1q MCA2603-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

mouse anti human C1q 伯乐 mouse anti human C1q MCA2603

2024-10-29

mouse anti human C1q

货号：MCA2603

规格：0.1 ml

市场价格：6248

产品类型：流式抗体

品牌：Bio-Rad

抗原：C1q

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：004-43.X (3R9/2)

荧光染料：Purified

产品介绍
Mouse anti human C1q antibody, clone 004-43.X (3R9/2),recognizes human complement component 1 q (C1q), a ~156 kDa secreted protein.C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A-, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation.C1q deficiency has been associated with lupus erythematosus and glomerulonephritis (Troedsonet al.2013).
产品详情
Target Species	Human
Product Form	Purified IgG - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from ascites
Buffer Solution	Borate buffered saline
Immunogen	Globular head domain of C1q, purified from human plasma.
Approx. Protein Concentrations	Current, batch-specific concentration 1.09 mg/ml
Preservative Stabilisers	0.09%Sodium Azide
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
推荐产品
Description	Product Code	Applications	Pack Size
Mouse IgG1 Negative Control	MCA928	F	100 Tests/1ml
文献
1.Petry, F. (1998) Molecular basis of hereditary C1q deficiency.Immunobiology. 199 (2): 286-94.2.Gershov, D.et al.(2000) C-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunity.J Exp Med. 192 (9): 1353-64.3.Castellano, G.et al.(2010) Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage.Am J Pathol. 176: 1648-59.4.Ma, W.et al.(2012) RAGE binds C1q and enhances C1q-mediated phagocytosis.Cell Immunol. 274: 72-82.5.Lachmann, N.et al.(2013) Systematic comparison of four cell- and Luminex-based methods for assessment of complement-activating HLA antibodies.Transplantation. 95 (5): 694-700.

技术参数

产品应用 Flow;IHC(F);IF;WB;IHC(P)

产品类型单克隆抗体

推荐用于 Flow;IHC(F);IF;WB;IHC(P)

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mouse anti human C1q 伯乐 mouse anti human C1q MCA2603

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