Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b BIO-RAD MCA2244PE Rat anti Mouse Lymphotoxin beta Receptor

2024-10-29

Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b

货号:MCA2244PE

规格:100 Tests

市场价格:3162

产品类型:流式抗体

品牌:Bio-Rad

抗原:Lymphotoxin beta Receptor

物种:小鼠

宿主:大鼠

抗体亚型:IgG2a

克隆号:5G11b

荧光染料:PE

产品介绍
Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11brecognizes murine Tumor necrosis factor receptor superfamily member 3, also known as lymphotoxin-beta receptor, LT beta R, or Tumor necrosis factor receptor superfamily member 3. Lymphotoxin beta receptor is 385 amino acid (415 aa including 30 aa signal peptide) ~50 kDa type 1, single pass transmembrane glycoprotein and member of the tumor necrosis factor family. LT beta R is primarily expressed on stromal cells and fibroblasts and at lower levels on myeloid cell lines. Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b recognizes surface expressed LT beta R.Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b is reported to be agonistic with respect to NF Kappa B activation, MIP-2 induction and IL-6 release (Hehlganset al.2003).Rat anti Mouse Lymphotoxin beta Receptor antibody, clone 5G11b is routinely tested on WEH164S cells.
产品详情
Target SpeciesMouse
Product FormPurified IgG conjugated to R. Phycoerythrin (RPE) - liquid
ReconstitutionReconstitute with 1.0 ml distilled water
PreparationPurified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers1% Bovine Serum Albumin
Fusion PartnersSpleen cells from immunized BALB/c mice were fused with cells of the X63/Ag8.653 mouse myeloma cell line
Max Ex/EmFluorophoreExcitation Max (nm)Emission Max (nm)
RPE 488nm laser496578
RegulatoryFor research purposes only
Guarantee6 months from date of despatch
存储条件
Prior to reconstitution store at +4℃. Following reconstitution store at +4℃.DO NOT FREEZE.This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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DescriptionProduct CodeApplicationsPack Size
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文献
1.Hehlgans Tet al.(2003) Activation of the lymphotoxin-beta receptor induces NFkappaB-dependent interleukin-6 and MIP-2 secretion in mouse fibrosarcoma cells.Eur Cytokine Netw. 14 (2): 103-7.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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