Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148 BIO-RAD MCA2086F Mouse anti Human CD18 (Activation Epito-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148 BIO-RAD MCA2086F Mouse anti Human CD18 (Activation Epito

2024-10-29

Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148

货号：MCA2086F

规格：0.1 mg

市场价格：2907

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD18 (Activation Epitope)

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：MEM-148

荧光染料：FITC

产品介绍
Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148recognizes an epitope on the human CD18 molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognized by Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148 is also exposed during dissociation of the CD11/CD18 by low pH.
产品详情
Target Species	Human
Product Form	Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09%Sodium Azide
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
FITC	490	525
Approx. Protein Concentrations	IgG concentration 0.1mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Drbal, K.et al.(2001) A proteolytically truncated form of free CD18, the common chain of leukocyte integrins, as a novel marker of activated myeloid cells.Blood. 98 (5): 1561-6.2.Luissint, A.C.et al.(2008) JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation.J Cell Biol. 183 (6): 1159-73.3.Feng, C.et al.(2011) Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1.J Leukoc Biol. 90: 313-21.4.Anogianaki, A.et al.(2007) Capsaicin an irritant anti-inflammatory compound.J Biol Regul Homeost Agents. 21: 1-4.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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Mouse anti Human CD18 (Activation Epitope) antibody, clone MEM-148 BIO-RAD MCA2086F Mouse anti Human CD18 (Activation Epito

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