Mouse anti Human CD222 antibody, clone MEM-238 BIO-RAD MCA2048F Mouse anti Human CD222 antibody, clone MEM-238-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

Mouse anti Human CD222 antibody, clone MEM-238 BIO-RAD MCA2048F Mouse anti Human CD222 antibody, clone MEM-238

2024-10-29

Mouse anti Human CD222 antibody, clone MEM-238

货号：MCA2048F

规格：0.1 mg

市场价格：3145

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD222

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：MEM-238

荧光染料：FITC

产品介绍
Mouse anti Human CD222 antibody, clone MEM-238recognizes human CD222, a 250 kDa transmembrane protein originally identified as the IGF II receptor. CD222 is ubiquitously expressed and is involved with internalization of a variety of ligands.Mouse anti Human CD222 antibody, clone MEM-238 recognizes an epitope located in the region between extracellular domains 2 and 5 (aa 192-697) of CD222 (Robertset al.2010).CD222 is primarily expressed intracellularly with a small percentage of molecules being located at the cell surface (5 - 10%).
产品详情
Target Species	Human
Product Form	Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
Preparation	Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09%Sodium Azide
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
FITC	490	525
Approx. Protein Concentrations	IgG concentration 0.1mg/ml
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application Name	Verified	Min Dilution	Max Dilution
Immunofluorescence	√	1/10
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Roberts, R.C.et al.(2010) Mistargeting of SH3TC2 away from the recycling endosome causes Charcot-Marie-Tooth disease type 4C.Hum Mol Genet. 19: 1009-18.2.Adachi, A.et al.(2010) Golgi-associated GSK3beta regulates the sorting process of post-Golgi membrane trafficking.J Cell Sci. 123: 3215-25.3.Godar, S.et al. (2002) CD222 (Mannose-6 phosphate / insulin-like growth factor II-receptor) Summary and Workshop Report.In Leucocyte Typing VII: White Cell Differentiation Antigens. Edited by Mason, D.et al.Oxford University Press. pp482-485.4.Rezgui, D.et al.(2009) Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth.J Mol Endocrinol. 42: 341-56.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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Mouse anti Human CD222 antibody, clone MEM-238 BIO-RAD MCA2048F Mouse anti Human CD222 antibody, clone MEM-238

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