mouse anti human CD326:Low Endotoxin 伯乐 MCA1870EL CD326抗体

2024-10-29

mouse anti human CD326:Low Endotoxin

货号:MCA1870EL

规格:0.5 mg

市场价格:5100

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD326

物种:人

宿主:小鼠

抗体亚型:IgG1, kappa

克隆号: VU-1D9

荧光染料:其它

产品介绍
Mouse anti Human CD326 antibody, clone VU-1D9recognizes epithelial cell adhesion molecule (Ep-CAM), a ~34 kDa cell surface antigen otherwise known as CD326, MOC31 or Ber-EP4. CD326 is a type 1 transmembrane glycoprotein, expressed on the basolateral cell membrane of the majority of epithelial tissues, with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. Ep-CAM expression has been reported to be a possible marker of early malignancy, with expression being increased in tumor cells.Ep-CAM expression has been reported to be a possible marker of early malignancy, with expression being increased in tumor cells, andde novoexpression being seen in dysplastic squamous epithelium.
产品详情

Target Species

Human

Product Form

Purified IgG - liquid

Preparation

Purified IgG prepared by affinity chromatography on Protein A

BufferSolution

Phosphate buffered saline

Preservative Stabilisers

None present

Carrier FreeYes
ImmunogenHG9 cell line (small cell lung carcinoma)
Approx. Protein Concentrations

1 mg/ml

Fusion PartnersSpleen cells from immunised mice were fused with cells of the mouse SP2/0 myeloma cell line

Regulatory

For research purposes only

Guarantee

12 monthsfrom date of despatch

存储条件
Store at -20oC only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry1/101/200
Immunohistology - Frozen
Immunohistology - Paraffin1
Immunoprecipitation
Western Blotting
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewedpublications or personal communications fromthe originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.1This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
  • Flow CytometryUse 10ul of the suggested working dilution to label 1x106cells in 100ul.
  • Histology Positive Control TissueLarge Bowel
同型
DescriptionProduct CodeApplicationsPack Size
Mouse IgG1 Negative Control:Low EndotoxinMCA928ELFlow0.5 mg
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文献
References for CD326 antibody1. Koga, Y.et al.(2008) Improved recovery of exfoliated colonocytes from feces using newly developed immunomagnetic beads.Gastroenterol Res Pract. 2008: 605273.2. Fillmore, C.M.et al.(2010) Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.Proc Natl Acad Sci U S A. 107 (50): 21737-42.3. Murakata, A.et al.(2011) Gene expression signature of the gross morphology in hepatocellular carcinoma.Ann Surg. 253: 94-100.4. Keller, P.J.et al.(2012) Defining the cellular precursors to human breast cancer.Proc Natl Acad Sci U S A. 109 (8): 2772-7.5. Jeong, H.T.et al.(2012) MRI features of hepatocellular carcinoma expressing progenitor cell markers.Liver Int. 32: 430-40.6. Armstrong, A.J.et al.(2019) Pharmacodynamic study of radium-223 in men with bone metastatic castration resistant prostate cancer.PLoS One. 14 (5): e0216934.Further Reading7. Winter, M.J.et al.(2003) The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology.Am J Pathol. 163 (6): 2139-48.

技术参数

产品应用 IHC(F); Flow; IP ;IHC(P) * ;WB

产品类型 Monoclonal Antibody

推荐用于 IHC(F); Flow; IP ;IHC(P) * ;WB

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