Mouse anti Dog CD3 BIO-RAD MCA1774GA Mouse anti Dog CD3

2024-10-29

Mouse anti Dog CD3

货号:MCA1774GA

规格:0.1 mg

市场价格:2491

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD3

物种:dog

宿主:小鼠

抗体亚型:IgG1

克隆号:CA17.2A12

荧光染料:Purified

产品介绍
Mouse anti Dog CD3 antibody, clone CA17.2A12recognizes the canine CD3 cell surface antigen, expressed by thymocytes and mature T lymphocytes. CD3 is engaged in the surface expression of the T-cell antigen receptor (TCR) and the signal transduction pathway resulting from MHC ligand binding to the TCR. CD3 is made up of a number of invariant subchains of the immunoglobulin superfamily.Mouse anti Dog CD3 clone CA17.2A12 is a valuable flow cytometric and immunohistologic tool for canine lymphoma detection of T-cell origin (Miniscalcoet al.2003).
产品详情
Target SpeciesDog
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein G
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09%Sodium Azide
ImmunogenAffinity enriched TCR/CD3 membrane proteins isolated from thymocytes and the T cell line CLGL-90
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
ELISA1/25
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Machado, G.F.et al.(2011) Intravascular Lymphomatosis in the Central Nervous System of Dogs: Immunohistochemical Investigation in Two CasesBraz J Vet Pathol 4: 47-512.Moore, P.F. and Rossitto, P.V. (1993) Development of monoclonal antibodies to canine T cell receptor complex (TCR/CD3) and their utilisation in the diagnosis of T cell neoplasia.Vet. Pathol. 30: 457. Abstract 1173.McDonough, S. P. and Moore, P. F. (2000) Clinical, hematologic, and immunophenotypic characterization of canine large granular lymphocytosis.Vet Pathol. 37:637-46.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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