Mouse anti Human CD70 BIO-RAD MCA1765GT Mouse anti Human CD70

2024-10-29

Mouse anti Human CD70

货号:MCA1765GT,MCA1765G

规格:25 µg,0.2 mg

市场价格:893,3740

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD70

物种:人

宿主:小鼠

抗体亚型:IgG1

克隆号:Bu69

荧光染料:Purified

产品介绍
Mouse anti Human CD70 antibody, clone Bu69recognises human CD70, also known as CD27 ligand (CD27-L) or Tumor necrosis factor ligand superfamily member 7. CD70 is a 193 amino acid ~29 kDa single pass type II transmembrane glycoprotein belonging to the tumour necrosis factor (TNF) family (UniProt: P32970).CD70 is expressed on a small number of activated T-cells and the majority of activated B-cells (Bowmanet al.1994). Interaction of CD70 with its receptor, CD27, is thought to play an important role in lymphocyte activation, proliferation, survival and differentiation (Hintzenet al.1994).Mouse anti Human CD70 antibody, clone Bu69 has been used for the inhibition of neural stem cell induced apoptosis of allogeneic T cellsin vitro(Leeet al.2013).
产品详情
Target SpeciesHuman
Product FormPurified IgG - liquid
PreparationPurified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Buffer SolutionPhosphate buffered saline
Preservative Stabilisers0.09%Sodium Azide
Carrier FreeYes
Approx. Protein ConcentrationsIgG concentration 1.0 mg/ml
RegulatoryFor research purposes only
Guarantee12 months from date of despatch
存储条件
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
Application NameVerifiedMin DilutionMax Dilution
Flow Cytometry1/50
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Garland Publishing. (1997) Leucocyte typing VI. White cell differentiation antigens.p522 - 42.Zambello, R.et al.(2000) Analysis of TNF-receptor and ligand superfamily molecules in patients with lymphoproliferative disease of granular lymphocytes.Blood. 96 (2): 647-54.3.Lee, E.M.et al.(2013) CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death.Stem Cell Res Ther. 4 (3): 56.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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