Mouse anti Human CD31:StarBright Blue 700

货号：MCA1738SBB700

规格：100 Tests/0.5ml

市场价格：3851

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD31

物种：人

宿主：小鼠

抗体亚型：IgG1

克隆号：WM59

荧光染料：StarBright Blue 700

类型：	单抗	同型对照：	IgG1
浓度：		用法：	5.0 µL/test(Flow)
免疫原性：

Mouse anti Human CD31 monoclonal antibody, clone WM59recognizes the human CD31 antigen, a ~130 kDa single pass type I transmembrane glycoprotein bearing sixC2 immunoglobulin domains. CD31 is expressed by all continuous endothelia including arteries, veins and non-sinusoidal capillaries, platelets,granulocytes and some lymphocytes. CD31 is not expressed by discontinuous endothelia such as hepatic sinusoids and splenic red pulp (Mulleret al.1989).CD31 is also known as PECAM-1.The binding epitope for mouse anti human CD31, clone WM59 has been mapped to the Ig-like domain 2 (Fawcettet al.1995).

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参考文献：

1.Cabañas, C.et al.(1989) Characterization of a novel myeloid antigen regulated during differentiation of monocytic cells.Eur J Immunol. 19 (8): 1373-8.2.Fawcett, J.et al. (1995) Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contacts.J Cell Biol. 128:1229-41.3.Paul, G.et al.(2012) The adult human brain harbors multipotent perivascular mesenchymal stem cells.PLoS One. 7: e35577.4.Stockinger, H.et al.(1990) Molecular characterization and functional analysis of the leukocyte surface protein CD31.J Immunol. 145 (11): 3889-97.5.DeLisser, H.M.et al.(1994) Molecular and functional aspects of PECAM-1/CD31.Immunol Today. 15 (10): 490-5.6.Urquhart, P.et al.(2007) Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow.J Pharmacol Exp Ther. 321 (2): 656-62.7.Reedquist, K.A.et al.(2000) The small GTPase, Rap1, mediates CD31-induced integrin adhesion.J Cell Biol. 148: 1151-8.8.Vernon-Wilson, E.F.et al.(2007) CD31 delays phagocyte membrane repolarization to promote efficient binding of apoptotic cells.J Leukoc Biol. 82: 1278-88.9.Johnston, A.et al.(2005) The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules.Clin Immunol. 114: 154-63.10.Hilbe Wet al.(2003) Immunohistochemical typing of non-small cell lung cancer on cryostat sections: correlation with clinical parameters and prognosis.J Clin Pathol. 56 (10): 736-41.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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