Rat anti mouse CD117:StarBright Violet 670 伯乐 MCA1365SBV670 CD117抗体

2024-10-29

Rat anti mouse CD117:StarBright Violet 670

货号:MCA1365SBV670

规格:100 Tests/0.5ml

市场价格:4106

产品类型:流式抗体

品牌:Bio-Rad

抗原:CD117

物种:小鼠

宿主:大鼠

抗体亚型:IgG2b

克隆号:2B8

荧光染料:StarBright Violet 670

类型:

单抗

同型对照:

IgG2b

浓度:

用法:

5.0 µL/test(Flow)

免疫原性:

IL-3 dependent mast cells.

Rat anti Mouse CD117 antibody, clone 2B8recognizes mouse CD117, a ~150 kDa cell surface molecule otherwise known as the Kit, or c-kit, receptor.Rat anti Mouse CD117 antibody, clone 2B8 recognizes an epitope within the extracellular region of CD117. In mice, CD117 is predominantly expressed on multipotent haematopoietic stem cells from the adult bone marrow and foetal liver.
数据

Figure A. StarBright Violet 440 conjugated Rat anti Mouse CD11b (MCA711SBV440). Figure B. StarBright Violet 440 conjugated Rat anti Mouse CD11b (MCA711SBV440) and StarBright Violet 670 conjugated Rat anti Mouse CD117 (MCA1365SBV670). All experiments performed on red cell lysed murine bone marrow gated on live single cells, in the presence of 10% mouse serum. Data acquired on the ZE5 Cell Analyzer.

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参考文献:

1.Fleming WHet al.(1993) Steel factor influences the distribution and activity of murine hematopoietic stem cellsin vivo.Proc Natl Acad Sci U S A. 90 (8): 3760-4.2.Rico-Vargas, S.A.et al.(1994) c-kit expression by B cell precursors in mouse bone marrow. Stimulation of B cell genesis by in vivo treatment with anti-c-kit antibody.J Immunol. 152 (6): 2845-52.3.Manova, K.et al.(1992) c-kit receptor and ligand expression in postnatal development of the mouse cerebellum suggests a function for c-kit in inhibitory interneurons.J Neurosci. 12 (12): 4663-76.4.Maeda, H.et al.(1992) Requirement of c-kit for development of intestinal pacemaker system.Development. 116 (2): 369-75.5.Takagi, M.et al.(1992) Stimulation of mouse connective tissue-type mast cells by hemopoietic stem cell factor, a ligand for the c-kit receptor.J Immunol. 148 (11): 3446-53.6.de Vries, P.et al.(1992) Thymus reconstitution by c-kit-expressing hematopoietic stem cells purified from adult mouse bone marrow.J Exp Med. 176 (6): 1503-9.

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