Canine IL-12 p40 ELISA Kit ELISA试剂盒,Canine IL-12 p40 ELISA Kit/犬IL-12 p40 ELISA试剂盒

2024-10-24

Canine IL-12 p40 ELISA Kit/犬IL-12 p40 ELISA试剂盒

货号:EC10RB,EC10RBX5,EC10RBX10

规格:96 Tests,5X96 Tests,10X96 tests

价格:6641,29884,57271

产品类型:Platinum ELISA

品牌:Thermo Fisher

物种:其它

宿主:其它

抗体亚型:其它

荧光染料:其它

灵敏度

24 pg/mL

检测范围24.58-6,000 pg/mL

样本类型/体积

血清 50 μL

血浆 50 μL

上清液 50 μL

操作时间

1 hr 20 min

测试时间

4 hr 45 min

Homogenous (no wash)

No

批间变异系数(CV)<12%
批内变异系数(CV)<10%

仪器设备

Colorimetric Microplate Reader 酶标仪

规格

5 x 96 Tests

组份

- 预包被96孔板

- 标准品

- 测定稀释浓缩液

- 生物素化检测抗体

- SAV-HRP

- 洗涤液

- 显色剂

- 终止液

- 胶板盖

储存温度

2-8℃

Protein nameIL-12 p40
Protein aliasesCLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40), interleukin-12 p40 subunit, Interleukin-12 subunit beta

物种(Tested)

试剂盒类型

Sandwich ELISA Kit

标记(染料)

HRP

检测抗体偶联物Biotin
Gene aliasesIL12B
Gene ID(Dog) 403976
UniProt ID(Dog) Q28268
Gene symbolIL12B
Canine IL-12 p40 quantitates canine IL-12 p40 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine IL-12 p40.犬IL-12 p40定量测定血清,血浆,上清液中的犬IL-12 p40。该检测试剂盒将只识别天然和重组犬IL-12 p40。Target information 靶标信息IL12B (IL-12 p40) encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kDa cytokine receptor like subunit encoded by this gene, and a 35 kDa subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.IL12B(IL-12 p40)编码白介素12的一个亚基,白细胞介素12是一种作用于T细胞和自然杀伤细胞的细胞因子,具有广泛的生物学活性。白介素12是由该基因编码的40 kDa细胞因子受体样亚基和IL12A编码的35 kDa亚基组成的二硫键连接的异二聚体。这种细胞因子由活化的巨噬细胞表达,而巨噬细胞可作为Th1细胞发育的重要诱导剂。已经发现这种细胞因子对于维持足够数量的记忆/效应Th1细胞以介导对细胞内病原体的长期保护很重要。在患有多发性硬化症(MS)的患者的中枢神经系统中观察到该基因的过表达,表明该细胞因子在疾病的发病机理中具有作用。据报道,该基因的启动子多态性与儿童特应性和非特应性哮喘的严重程度有关。For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.仅供研究使用。 不用于诊断过程。 未经明确授权不得转售。

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