BIO-RAD MCA711SBB700 Rat anti Mouse CD11b antibody, clone 5C6,Rat anti Mouse CD11b antibody, clone 5C6-试剂- bio-rad伯乐一级代理 |伯乐Aminex |伯乐电泳槽1658001| 伯乐ddPCR bio-rad授权代理商、biorad伯乐qpcr仪

BIO-RAD MCA711SBB700 Rat anti Mouse CD11b antibody, clone 5C6,Rat anti Mouse CD11b antibody, clone 5C6

2024-10-22

Rat anti Mouse CD11b antibody, clone 5C6

货号：MCA711SBB700

规格：100 Tests/0.5ml

价格：3596

产品类型：流式抗体

品牌：Bio-Rad

抗原：CD11b

物种：小鼠

宿主：大鼠

抗体亚型：IgG2b

克隆号：5C6

荧光染料：StarBright Blue 700

产品介绍
Rat anti Mouse CD11b antibody, clone 5C6recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles.Rat anti Mouse CD11b antibody, clone 5C6 immunoprecipitates a heterodimer of ~165 and ~95 kDa. This clone also exhibits various functional properties, reportedly inhibiting adhesionin vitroand inflammatory recruitmentin vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
产品详情
Target Species	Mouse
Product Form	Purified IgG conjugated to StarBright Blue 700 - liquid
Preparation	Purified IgG prepared by ion exchange chromatography
Reconstitution	Reconstitute with 1.0 ml distilled waterCare should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
Buffer Solution	Phosphate buffered saline
Preservative Stabilisers	0.09% Sodium Azide (NaN3)1% Bovine Serum Albumin0.1% Pluronic F680.1% PEG 3350
Immunogen	Thioglycollate-elicited peritoneal macrophages (TPM)
Fusion Partners	Spleen cells from AO rats were fused with cells of the Y3 rat myeloma cell line
Max Ex/Em	Fluorophore	Excitation Max (nm)	Emission Max (nm)
StarBright Blue 700	470	700
Regulatory	For research purposes only
Guarantee	12 months from date of despatch
存储条件
Store at +4°C. DO NOT FREEZE.This product should be stored undiluted.
应用
Application Name	Verified	Min Dilution	Max Dilution
Flow Cytometry	√	Neat
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit theantibody protocolspage.Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
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文献
1.Dohi, K.et al.(2010) Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury.J Neuroinflammation. 7: 41.2.Engwerda, C.R.et al.(2002) Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria.J Exp Med. 195: 1371-7.3.Heneka, M.T.et al.(2010) Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine.Proc Natl Acad Sci U S A. 107: 6058-63.4.Kim, D.et al.(2010) NADPH oxidase 2-derived reactive oxygen species in spinal cord microglia contribute to peripheral nerve injury-induced neuropathic pain.Proc Natl Acad Sci U S A. 107: 14851-6.

技术参数

产品应用 Flow

产品类型 Monoclonal Antibody

推荐用于 Flow

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BIO-RAD MCA711SBB700 Rat anti Mouse CD11b antibody, clone 5C6,Rat anti Mouse CD11b antibody, clone 5C6

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